Bronze level automatically awarded US beta

This data has achieved Bronze level on 22 October 2015 which means this data makes a great start at the basics of publishing open data.

A Nanodroplet Processor for Advanced Microencapsulated Drug Formulations Project

Description

During this Phase II program we propose to build on the key aspects of the nanodroplet encapsulation technology to demonstrate optimized formulation and encapsulation of protein drugs. The ability of the nanodroplet generator to produce nanoscale drug "containers" with designer characteristics provides us with a distinct advantage in targeting protein containing vesicles to diseased cells and organs. We plan to target cancerous cells and tumors using our engineered drug vesicles, with specifically designed lipid outer layers as well as targeted surface functionalization to improve drug uptake by the cells, reduce toxicity, and otherwise improve safety and efficacy. The optimized vesicles will result in improved stability and enhanced control of pharmacokinetics in both cell lines and animal models.The nanodroplet platform will be scaled up to produce gram quantities of engineered vesicles with a monodisperse size distribution and a target size of 200nm.

General Information

Legal Information

This dataset has been created by US Government which means it is required to be in the public domain. However US copyright law only allows open access by US citizens, we have assumed the data is equivalently licensed as CC0 for the rest of the world as this is in the spirit of the US Government’s Open Data policy.

  • The rights statement is at

    http://catalog.data.gov/dataset/a-nanodroplet-processor-for-advanced-microencapsulated-drug-formulations-project Do you think this data is incorrect? Let us know

  • Outside the US, this data is available under

    Creative Commons CCZero Do you think this data is incorrect? Let us know

  • There are

    yes, and the rights are all held by the same person or organisation Do you think this data is incorrect? Let us know

  • The content is available under

    Creative Commons CCZero Do you think this data is incorrect? Let us know

  • The rights statement includes data about

    its data licence Do you think this data is incorrect? Let us know

  • This data contains

    no data about individuals Do you think this data is incorrect? Let us know

Practical Information

  • The data appears in this collection

    http://catalog.data.gov/organization/nasa-gov Do you think this data is incorrect? Let us know

  • The accuracy or relevance of this data will

    go out of date but it is timestamped Do you think this data is incorrect? Let us know

  • The data is

    backed up offsite Do you think this data is incorrect? Let us know

Technical Information

  • This data is published at

    http://techport.nasa.gov/xml-api/5776 Do you think this data is incorrect? Let us know

  • This data is

    machine-readable Do you think this data is incorrect? Let us know

  • The format of this data is

    a standard open format Do you think this data is incorrect? Let us know

Social Information

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  • Find out how to contact someone about this data at

    http://catalog.data.gov/dataset/a-nanodroplet-processor-for-advanced-microencapsulated-drug-formulations-project Do you think this data is incorrect? Let us know

  • Find out how to suggest improvements to publication at

    http://www.data.gov/issue/?media_url=http://catalog.data.gov/dataset/a-nanodroplet-processor-for-advanced-microencapsulated-drug-formulations-project Do you think this data is incorrect? Let us know