Bronze level automatically awarded US beta

This data has achieved Bronze level on 25 October 2015 which means this data makes a great start at the basics of publishing open data.

Illuminating the Druggable Genome (IDG)

Description

Results from the Human Genome Project revealed that the human genome contains 20,000 to 25,000 genes. A gene contains (encodes) the information that each cell uses to make (express) a protein, which is essential for the body to function properly. Abnormal protein expression is associated with many human diseases, which makes proteins key targets for therapeutic agents. Approximately 3,000 genes are considered part of the "druggable genome," a set of genes encoding proteins that scientists can or predict they can modulate using experimental small molecule compounds. Yet only about 10 percent of these genes encode proteins that have been targeted successfully by an approved drug. Therefore, a large number of proteins remain for scientists to explore as potential therapeutic targets. The vast majority of the druggable genome encodes four key protein families: G-protein-coupled receptors, nuclear receptors, ion channels and kinases. Researchers lack crucial knowledge about the function of many proteins from these families and their roles in health and disease. Better understanding of how these proteins work could shed light on new avenues of investigation for basic science and therapeutic discovery.

General Information

Legal Information

This dataset has been created by US Government which means it is required to be in the public domain. However US copyright law only allows open access by US citizens, we have assumed the data is equivalently licensed as CC0 for the rest of the world as this is in the spirit of the US Government’s Open Data policy.

  • The rights statement is at

    http://catalog.data.gov/dataset/illuminating-the-druggable-genome-idg Do you think this data is incorrect? Let us know

  • Outside the US, this data is available under

    Creative Commons CCZero Do you think this data is incorrect? Let us know

  • There are

    yes, and the rights are all held by the same person or organisation Do you think this data is incorrect? Let us know

  • The content is available under

    Creative Commons CCZero Do you think this data is incorrect? Let us know

  • The rights statement includes data about

    its data licence Do you think this data is incorrect? Let us know

  • This data contains

    no data about individuals Do you think this data is incorrect? Let us know

Practical Information

  • The data appears in this collection

    http://catalog.data.gov/organization/federal-laboratory-consortium Do you think this data is incorrect? Let us know

  • The accuracy or relevance of this data will

    go out of date but it is timestamped Do you think this data is incorrect? Let us know

  • The data is

    backed up offsite Do you think this data is incorrect? Let us know

Social Information

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  • Find out how to contact someone about this data at

    http://catalog.data.gov/dataset/illuminating-the-druggable-genome-idg Do you think this data is incorrect? Let us know

  • Find out how to suggest improvements to publication at

    http://www.data.gov/issue/?media_url=http://catalog.data.gov/dataset/illuminating-the-druggable-genome-idg Do you think this data is incorrect? Let us know